In recent years, the increasing prevalence of chronic diseases such as cardiovascular disease and diabetes has increased the demand for advanced drug delivery systems that allow patients to self-administer their medications. Self-administration systems, such as pre-filled syringes, allow the patient to manage their health condition without the need for a healthcare clinician to assist with medication management.
A pre-filled syringe is a packaging system that comes with an accurate pre-filled dose of parenteral medication, which offers many benefits to patients, including accuracy of dosing, self-administration and reduced risk of infection. With the development of pre-filled syringes, the number of hospital visits due to disease treatment has significantly decreased.
To meet the growing demand, several pharmaceutical companies have developed pre-filled syringes. According to a recent report by Roots Analysis, the global pre-filled syringe market is expected to grow from $3,024 million in 2024 to $4,972 million in 2035 due to the increasing adoption of self-administration devices. The pre-filled syringes market will grow at a high compound annual growth rate (CAGR) of 4.5% between 2024 and 2035.
Global market for prefilled syringes
According to Roots Analysis, there are nearly 35 players in the pre-filled syringe market with the technical expertise to develop syringes for the self-administration of innovative drugs. Currently, there are nearly 125 prefilled syringe products on the prefilled syringe market. It is worth noting that about 70% of these prefilled syringes use glass as the barrel material. Additionally, 90% of prefilled syringes developed by key players are in single-chamber format. However, the growing shift towards dual-chamber prefilled syringes to increase drug stability and shelf life is attracting companies’ interest in this area. Overall, this market appears to be highly fragmented, with very small, small, medium, large and very large manufacturers present.
Technological developments that drive growth
Many players in this field are researching different materials to improve the shelf life, stability and quality of medicines. Technological innovations in materials help eliminate interactions between many stored therapeutic drugs and packaging materials, such as silicone residues and tungsten. For example, SCHOTT AG’s Syria BioPure silicone-free syringes combined with ImproJect plungers from WL Gore & Associated provide silicone-free products compatible with highly sensitive therapeutic drugs.
Safety mechanisms of the needle
Pre-filled syringes cause needlestick injuries, mainly due to accidental punctures during drug administration and handling of pre-filled syringes. To address this concern, several players in this field have incorporated retractable needles and begun using needle guard systems that automatically retract into the syringe container after injection. For example, the Ompi syringes marketed by Stevanato provide an integrated safety system for syringes with needles.
Smart pre-filled syringes
Currently, the pre-filled syringe market is witnessing several advancements such as the integration of smart technologies that help increase functional value and enable data tracking. For example, the Med-ic® SyringePack ECM™ helps monitor the temperature of prefilled syringes, ensuring product integrity at the time of administration. In addition, many industry leaders are focusing on automated fill/completion operations to provide greater efficiency, data integrity and greater flexibility.
Major Milestones in the Prefilled Syringes Market
Roots Analysis reports that the Prefilled Syringes market is expected to witness significant growth due to various increasing development activities. Below are some notable examples of key developments in this area:
- In July 2023, Fresenius Kabi launched its first ready-to-administer prefilled syringes (Simplist®) containing fentanyl citrate injection.
- In May 2023, Becton Dickinson expanded the customer availability of its pre-filled flushing syringes with the help of an integrated disinfection unit.
- In May 2023, SCHOTT AG launched its advanced pre-filled syringes made of pharmaceutical grade polymers for the delivery of cryogenic drugs.
- In May 2023, Medefill launched Atropine Sulfate Injection USP 1 mg/10 mL for the treatment of bradyasystolic cardiac arrest.
It is worth noting here that in August 2023, Becton Dickinson, the Children’s Investment Fund Foundation, Pfizer and the Bill & Melinda Gates Foundation expanded their collaboration, which aims to deliver more than 320 million doses of Pfizer’s injectable contraceptive, namely Becton’s Sayana® Press. Dickinson Uniject™ Automatic Disabling Preload Injection System 2030.
Regional dynamics: Europe is the market leader
According to Roots Analysis, Europe is expected to hold a significant (50%) share of the prefilled syringes market in 2024, followed by North America and Asia Pacific. The dominance of the global region remains unchanged and the market in Asia Pacific is expected to expand at a higher CAGR of 7% during 2024-2035.
As key players adopt advanced technologies to develop innovative automated drug delivery systems, the prefilled syringes market is expected to grow significantly at a steady pace. Some notable examples of leading industry players in the market include Credence MedSystems, Gerresheimer, JOPharma, Medefil, Mitsubishi Gas Chemical, Novartis, Pfizer, SCHOTT, Stevanato, Taisei Kako, and Vetter Pharma.
Concluding remarks
In a nutshell, the market for prefilled syringes is growing exponentially as the demand for self-injectors to improve patient compliance increases. However, prefilled syringes present several challenges, such as the risk of needle stick injuries and contamination due to mishandling. Therefore, the key players are currently focusing on improving the biocompatibility of drugs and the constant concerns that patients can accurately administer doses without seeking the help of healthcare professionals. Additionally, growing demand for automated drug delivery systems and growing support from regulatory agencies such as the FDA are encouraging industry leaders to develop novel prefilled syringe solutions. Continuous efforts and proliferation of these tools have become the main reasons for growth in this area and this trend will continue during the forecast period.
Please read the full report for more information Market of pre-filled syringeswhich details the unique dynamics of this market, providing insight into the historical period (2023-2024) and forecasting trends for the period 2024-2035.
About the author
Simran Kaur is a senior analyst who has been working as an integral part of the Roots Analysis team since 2020. He obtained a master’s and bachelor’s degree in pharmacy from a prestigious institution, and started his professional journey with strong scientific foundations and an interest in life. field of sciences. His desire to learn more about emerging trends, regulatory dynamics and technological advancements enables him to provide comprehensive analyses.
About Roots Analysis
Roots Analysis world leader in pharmaceutical and biotechnology market research. For more than a decade, working with over 750 clients worldwide, including Fortune 500 companies, startups, academia, venture capitalists and strategic investors, Roots Analysis brings a highly analytical and data-driven perspective to a network of over 450,000 industry leaders . stakeholders looking for authentic market insights. All reports published by the company are structured in such a way that the reader develops a thorough perspective on the given topic.